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Ferrari R, Cucchini F, Dilisa F, and et al
It plays a critical role in the initiation of cellular senescence by causing cell cycle arrest in response to a variety of stressors, such as oxidative stress, DNA damage, and telomere attrition (Beck et al
At clinical doses under supervision, the most common side effects are mild nausea in the first week (typically resolves by day 7 to 10), injection site reactions (redness, minor swelling, localized soreness lasting 24 hours), and occasional transient fatigue or mild headache in the first few days
It plays a crucial role in cellular energy production by transporting fatty acids into the mitochondria, where they are converted into usable energy
MSC-EVs were efficiently internalized by mouse BECs and restore BBB strength
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